The magazine of preventive health and longevity.
Sourced, fact-checked articles written by doctors and experts, to understand, prevent and act every day.
Metabolic Flexibility: Definition, Simple Test and How to Act
Metabolic flexibility is the body's ability to switch between fat and carbohydrate as fuel. Here is how it is measured, from the…
Acarbose or Metformin: Which One for Longevity?
Acarbose and metformin both extend lifespan in mice, but their mechanisms, human evidence and side effects differ. Here is what the research…
Water Retention: 6 Proven Causes and Essential Fixes
Water retention causes fluid to build up in the ankles, hands or face, often from excess salt, heat or hormonal shifts. Simple…
Spirulina or Chlorella: Which One Should You Choose for Longevity?
Spirulina and chlorella are often sold as similar longevity superfoods, but randomized trials show different strengths: spirulina for cholesterol and blood pressure,…
Calorie Restriction and Longevity: How Much Should You Actually Cut?
Calorie restriction can slow biological aging, but how much reduction is realistic and safe? CALERIE, the Wisconsin monkey cohort and the Waziry…
Metformin Longevity: 3 Scientific Proofs to Know
Metformin, a diabetes drug, is studied for its effects on longevity. Here are 3 scientific proofs behind the metformin longevity hypothesis and…
Plant Protein or Animal Protein: Which Should You Choose?
Plant protein and animal protein both supply essential amino acids, but studies on mortality, muscle synthesis and long term health show they…
6 Proven Causes of Obesity and Weight Gain
Genetics, sleep, ultra-processed food and the gut microbiome are among six proven causes of obesity, each backed by peer-reviewed research explaining how…
Keto Diet: 5 Proven Effects on Weight and Metabolism
The keto diet is a very low carbohydrate, high fat diet. Trials show it can speed weight loss, curb appetite and improve…