The magazine of preventive health and longevity.
Sourced, fact-checked articles written by doctors and experts, to understand, prevent and act every day.
Metabolic Flexibility: Definition, Simple Test and How to Act
Metabolic flexibility is the body's ability to switch between fat and carbohydrate as fuel. Here is how it is measured, from the…
Amyloidosis: How These Protein Deposits Weaken the Heart
Amyloidosis occurs when misfolded proteins form fibrils that stiffen the heart. The transthyretin form affects 6 to 13% of older heart failure…
Sedentary Behavior: How Sitting Damages the Heart and Muscles
Sedentary behavior damages the heart and muscles even in people who exercise. Beyond 10.6 hours of sitting a day, heart failure risk…
Low Blood Pressure: 5 Proven Causes of Hypotension After 60
Low blood pressure after 60 rarely shows up as a single reading: it strikes on standing, after meals or in hot weather.…
Macular Degeneration: 5 Proven Levers to Protect Your Retina From Aging
Macular degeneration affects about 8% of people in France and is the leading cause of visual disability after 50. Five levers, from…
Acarbose or Metformin: Which One for Longevity?
Acarbose and metformin both extend lifespan in mice, but their mechanisms, human evidence and side effects differ. Here is what the research…
Vaccination and Age: 5 Proven Effects on Immunity
After 65, vaccination protects less well because the immune system remodels itself. Here is why, and how targeted formulations and daily habits…
Swimming Benefits: 5 Proven Effects on the Heart and Joints
Swimming benefits the heart and joints alike, lowering blood pressure and easing arthritis pain, according to large British cohort studies and randomized…
Oxytocin: Why Does This Hormone Protect Your Health?
Oxytocin lowers cortisol and supports heart health through touch and social bonds, according to clinical trials in humans.