The magazine of preventive health and longevity.
Sourced, fact-checked articles written by doctors and experts, to understand, prevent and act every day.
Spermidine and Longevity: What the Science Shows
Spermidine is a natural polyamine that activates cellular autophagy and extends lifespan in yeast, flies, worms and mice, while large human cohorts…
Japanese Mushrooms: What the Science Says About Polyamines and Longevity
Japanese mushrooms such as shiitake, maitake and enoki are rich in polyamines linked to autophagy, and higher intake is tied to lower…
Heatwave and Aging: Protecting a Body That Is Growing Older
Heatwave and aging combine to strain the heart, kidneys and hydration of older adults. Here is why extreme heat is risky, and…
Deep Sleep and the Brain’s Nightly Cleanup
Deep sleep triggers the brain's glymphatic cleaning system, clearing toxic proteins tied to neurodegenerative disease. Here are 6 proven keys to protect…
Intermittent Fasting: The Complete, Evidence Based Guide (2026)
16/8, 5:2, autophagy: here is what the science really says about the real benefits and limits of intermittent fasting for weight, metabolism…